Reaction Details |
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Target | DNA damage-inducible transcript 3 protein |
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Ligand | BDBM68024 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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IC50 | 450±n/a nM |
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Citation | PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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DNA damage-inducible transcript 3 protein |
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Name: | DNA damage-inducible transcript 3 protein |
Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 19175.17 |
Organism: | Mus musculus |
Description: | gi_160707929 |
Residue: | 168 |
Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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BDBM68024 |
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n/a |
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Name | BDBM68024 |
Synonyms: | 2-[2-[(3,4-dimethoxyphenyl)methyl]-1-benzimidazolyl]-N'-[(E)-(4-methyl-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]acetohydrazide | 2-[2-[(3,4-dimethoxyphenyl)methyl]benzimidazol-1-yl]-N'-[(E)-(4-methyl-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)methyl]ethanehydrazide | 2-[2-[(3,4-dimethoxyphenyl)methyl]benzimidazol-1-yl]-N'-[(E)-(4-methyl-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]acetohydrazide | MLS000587847 | N'-[(E)-(6-keto-4-methyl-cyclohexa-2,4-dien-1-ylidene)methyl]-2-(2-veratrylbenzimidazol-1-yl)acetohydrazide | SMR000211867 | [2-(3,4-Dimethoxy-benzyl)-benzoimidazol-1-yl]-acetic acid [1-(2-hydroxy-4-methyl-phenyl)-meth-(E)-ylidene]-hydrazide | cid_5936719 |
Type | Small organic molecule |
Emp. Form. | C26H26N4O4 |
Mol. Mass. | 458.509 |
SMILES | COc1ccc(Cc2nc3ccccc3n2CC(=O)NN=Cc2ccc(C)cc2O)cc1OC |w:20.21| |
Structure |
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