| Reaction Details |
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 | Report a problem with these data |
| Target | DNA damage-inducible transcript 3 protein |
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| Ligand | BDBM43647 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress |
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| IC50 | >10000±n/a nM |
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| Citation |  PubChem, PC Dose-response primary assay and counterscreen assay for HTS small molecule inhibitors of CHOP to regulate the unfolded protein response to ER stress PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA damage-inducible transcript 3 protein |
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| Name: | DNA damage-inducible transcript 3 protein |
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| Synonyms: | Chop | Chop10 | DDIT3_MOUSE | Ddit3 | Gadd153 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 19175.17 |
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| Organism: | Mus musculus |
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| Description: | gi_160707929 |
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| Residue: | 168 |
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| Sequence: | MAAESLPFTLETVSSWELEAWYEDLQEVLSSDEIGGTYISSPGNEEEESKTFTTLDPASL
AWLTEEPGPTEVTRTSQSPRSPDSSQSSMAQEEEEEEQGRTRKRKQSGQCPARPGKQRMK
EKEQENERKVAQLAEENERLKQEIERLTREVETTRRALIDRMVSLHQA
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| BDBM43647 |
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| n/a |
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| Name | BDBM43647 |
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| Synonyms: | (4E)-4-(1H-indol-2-ylmethylene)-5-methyl-2-phenyl-2,4-dihydro-3H-pyrazol-3-one | 4-[(Z)-2-indolylidenemethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one | 4-[(Z)-indol-2-ylidenemethyl]-5-methyl-2-phenyl-1H-pyrazol-3-one | 4-[(Z)-indol-2-ylidenemethyl]-5-methyl-2-phenyl-3-pyrazolin-3-one | MLS000724469 | SMR000306063 | cid_6614727 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15N3O |
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| Mol. Mass. | 301.3419 |
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| SMILES | Cc1[nH]n(-c2ccccc2)c(=O)c1C=C1C=c2ccccc2=N1 |w:13.14,c:24,t:17| |
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| Structure | 
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