Reaction Details | |||
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Target | Glycogen synthase kinase-3 beta | ||
Ligand | BDBM69203 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Luminescence Cell-Free Homogeneous Dose Retest to Identify Inhibitors of Glycogen Synthase Kinase-3 beta Activity | ||
EC50 | >300000±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Solution Info, Assay Method | ||
Glycogen synthase kinase-3 beta | |||
Name: | Glycogen synthase kinase-3 beta | ||
Synonyms: | GSK-3 beta | GSK-3, beta | GSK3B | GSK3B_HUMAN | Glycogen synthase kinase 3 beta (GSK3B) | Glycogen synthase kinase 3-beta (GSK3B) | Glycogen synthase kinase-3 beta (GSK-3B) | Glycogen synthase kinase-3 beta (GSK3 Beta) | Glycogen synthase kinase-3 beta (GSK3B) | Glycogen synthase kinase-3B (GSK-3B) | Glycogen synthase kinase-3beta (GSK3B) | Serine/threonine-protein kinase GSK3B | ||
Type: | Enzyme | ||
Mol. Mass.: | 46756.38 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P49841 | ||
Residue: | 420 | ||
Sequence: |
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BDBM69203 | |||
n/a | |||
Name | BDBM69203 | ||
Synonyms: | 2-[4-(dimethylamino)-1-pyridin-1-iumyl]-1-(10-phenothiazinyl)ethanone;chloride | 2-[4-(dimethylamino)pyridin-1-ium-1-yl]-1-phenothiazin-10-yl-ethanone;chloride | 2-[4-(dimethylamino)pyridin-1-ium-1-yl]-1-phenothiazin-10-ylethanone;chloride | MLS000689071 | SMR000283191 | cid_16192708 | ||
Type | Small organic molecule | ||
Emp. Form. | C21H20N3OS | ||
Mol. Mass. | 362.467 | ||
SMILES | C[N+](C)=c1ccn(CC(=O)N2c3ccccc3Sc3ccccc23)cc1 |(7.44,13.06,;6.14,12.3,;4.83,13.06,;6.14,10.79,;7.44,10.04,;7.44,8.53,;6.14,7.78,;6.14,6.27,;4.83,5.51,;3.52,6.27,;4.83,4,;3.52,3.25,;2.18,4.06,;.81,3.28,;.81,1.71,;2.18,.94,;3.52,1.74,;4.83,.99,;6.14,1.74,;7.49,.94,;8.85,1.71,;8.85,3.28,;7.49,4.06,;6.14,3.25,;4.83,8.53,;4.83,10.04,)| | ||
Structure | ![]() |