Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM72246

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM72246

n/a

Name

BDBM72246

Synonyms:

3-(4-fluorophenyl)-3-(4-methoxyphenyl)-N-(phenylmethyl)-1-propanamine | 3-(4-fluorophenyl)-3-(4-methoxyphenyl)-N-(phenylmethyl)propan-1-amine | Benzyl-[3-(4-fluoro-phenyl)-3-(4-methoxy-phenyl)-propyl]-amine | MLS000331585 | N-benzyl-3-(4-fluorophenyl)-3-(4-methoxyphenyl)propan-1-amine | SMR000220686 | benzyl-[3-(4-fluorophenyl)-3-(4-methoxyphenyl)propyl]amine | cid_4359400

Type

Small organic molecule

Emp. Form.

C23H24FNO

Mol. Mass.

349.4412

SMILES

COc1ccc(cc1)C(CCNCc1ccccc1)c1ccc(F)cc1

Structure