Ki Summary

Reaction Details

Report a problem with these data

Target

Heat shock factor protein 1

Ligand

BDBM72252

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM72252

n/a

Name

BDBM72252

Synonyms:

8-(6-ethoxy-3-tosyl-4-quinolyl)-1,4-dioxa-8-azaspiro[4.5]decane | 8-[6-ethoxy-3-(4-methylphenyl)sulfonyl-4-quinolinyl]-1,4-dioxa-8-azaspiro[4.5]decane | 8-[6-ethoxy-3-(4-methylphenyl)sulfonyl-quinolin-4-yl]-1,4-dioxa-8-azaspiro[4.5]decane | 8-[6-ethoxy-3-(4-methylphenyl)sulfonylquinolin-4-yl]-1,4-dioxa-8-azaspiro[4.5]decane | MLS000722172 | SMR000236813 | cid_5640523

Type

Small organic molecule

Emp. Form.

C25H28N2O5S

Mol. Mass.

468.565

SMILES

CCOc1ccc2ncc(c(N3CCC4(CC3)OCCO4)c2c1)S(=O)(=O)c1ccc(C)cc1

Structure