| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
|---|
| Ligand | BDBM72253 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) |
|---|
| EC50 | >260000±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Heat shock factor protein 1 |
|---|
| Name: | Heat shock factor protein 1 |
|---|
| Synonyms: | HSF1_MOUSE | Hsf1 | Hsf1 protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 57208.68 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | P38532 |
|---|
| Residue: | 525 |
|---|
| Sequence: | MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
|
|
|
|---|
| BDBM72253 |
|---|
| n/a |
|---|
| Name | BDBM72253 |
|---|
| Synonyms: | 3-(4-chlorophenyl)sulfonyl-6-fluoranyl-1-[(4-methylphenyl)methyl]quinolin-4-one | 3-(4-chlorophenyl)sulfonyl-6-fluoro-1-(4-methylbenzyl)-4-quinolone | 3-(4-chlorophenyl)sulfonyl-6-fluoro-1-[(4-methylphenyl)methyl]-4-quinolinone | 3-(4-chlorophenyl)sulfonyl-6-fluoro-1-[(4-methylphenyl)methyl]quinolin-4-one | MLS000722119 | SMR000236778 | cid_2137248 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H17ClFNO3S |
|---|
| Mol. Mass. | 441.902 |
|---|
| SMILES | Cc1ccc(Cn2cc(c(=O)c3cc(F)ccc23)S(=O)(=O)c2ccc(Cl)cc2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
