Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM72257

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

55300±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM72257

n/a

Name

BDBM72257

Synonyms:

2-(2-furoylamino)benzoic acid [2-(1H-indol-3-yl)-2-keto-ethyl] ester | 2-[[2-furanyl(oxo)methyl]amino]benzoic acid [2-(1H-indol-3-yl)-2-oxoethyl] ester | MLS000335869 | SMR000253623 | [2-(1H-indol-3-yl)-2-oxidanylidene-ethyl] 2-(furan-2-ylcarbonylamino)benzoate | [2-(1H-indol-3-yl)-2-oxoethyl] 2-(furan-2-carbonylamino)benzoate | cid_2122509

Type

Small organic molecule

Emp. Form.

C22H16N2O5

Mol. Mass.

388.3728

SMILES

O=C(COC(=O)c1ccccc1NC(=O)c1ccco1)c1c[nH]c2ccccc12

Structure