Ki Summary

Reaction Details

Report a problem with these data

Target

Heat shock factor protein 1

Ligand

BDBM72277

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

42390±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM72277

n/a

Name

BDBM72277

Synonyms:

2-azanyl-4-[2,3-bis(chloranyl)phenyl]-5-ethanoyl-4H-pyrano[3,2-b]indole-3-carbonitrile;ethanol | 5-Acetyl-2-amino-4-(2,3-dichloro-phenyl)-4,5-dihydro-pyrano[3,2-b]indole-3-carbonitrile | 5-acetyl-2-amino-4-(2,3-dichlorophenyl)-4H-pyran[3,2-b]indole-3-carbonitrile;ethanol | 5-acetyl-2-amino-4-(2,3-dichlorophenyl)-4H-pyrano[3,2-b]indole-3-carbonitrile;ethanol | MLS000587531 | SMR000211560 | cid_15944864

Type

Small organic molecule

Emp. Form.

C20H13Cl2N3O2

Mol. Mass.

398.242

SMILES

CC(=O)n1c2C(C(C#N)C(=N)Oc2c2ccccc12)c1cccc(Cl)c1Cl

Structure