| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Heat shock factor protein 1 |
|---|
| Ligand | BDBM72278 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) |
|---|
| EC50 | 7510±n/a nM |
|---|
| Citation |  PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Heat shock factor protein 1 |
|---|
| Name: | Heat shock factor protein 1 |
|---|
| Synonyms: | HSF1_MOUSE | Hsf1 | Hsf1 protein |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 57208.68 |
|---|
| Organism: | Mus musculus |
|---|
| Description: | P38532 |
|---|
| Residue: | 525 |
|---|
| Sequence: | MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS
|
|
|
|---|
| BDBM72278 |
|---|
| n/a |
|---|
| Name | BDBM72278 |
|---|
| Synonyms: | 2-[[1-(2-cyanoethyl)-3-(4-phenylphenyl)-4-pyrazolyl]methylidene]propanedinitrile | 2-[[1-(2-cyanoethyl)-3-(4-phenylphenyl)pyrazol-4-yl]methylene]malononitrile | 2-[[1-(2-cyanoethyl)-3-(4-phenylphenyl)pyrazol-4-yl]methylidene]propanedinitrile | MLS000722318 | SMR000235969 | cid_4111548 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H15N5 |
|---|
| Mol. Mass. | 349.388 |
|---|
| SMILES | N#C[#6]-[#6]-n1cc(\[#6]=[#6](\C#N)C#N)c(n1)-c1ccc(cc1)-c1ccccc1 |
|---|
| Structure | 
|
|---|
Search and Browse
