Ki Summary

Reaction Details

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Target

Heat shock factor protein 1

Ligand

BDBM72283

Substrate/Competitor

n/a

Meas. Tech.

Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1)

EC50

>260000±n/a nM

Citation

PubChem, PC Luminescence Cell-Based Dose Retest to Identify Potentiators of Heat Shock Factor 1 (HSF1) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Heat shock factor protein 1

Name:

Heat shock factor protein 1

Synonyms:

HSF1_MOUSE | Hsf1 | Hsf1 protein

Type:

Enzyme Catalytic Domain

Mol. Mass.:

57208.68

Organism:

Mus musculus

Description:

P38532

Residue:

525

Sequence:

MDLAVGPGAAGPSNVPAFLTKLWTLVSDPDTDALICWSPSGNSFHVFDQGQFAKEVLPKY
FKHNNMASFVRQLNMYGFRKVVHIEQGGLVKPERDDTEFQHPCFLRGQEQLLENIKRKVT
SVSTLKSEDIKIRQDSVTRLLTDVQLMKGKQECMDSKLLAMKHENEALWREVASLRQKHA
QQQKVVNKLIQFLISLVQSNRILGVKRKIPLMLSDSNSAHSVPKYGRQYSLEHVHGPGPY
SAPSPAYSSSSLYSSDAVTSSGPIISDITELAPTSPLASPGRSIDERPLSSSTLVRVKQE
PPSPPHSPRVLEASPGRPSSMDTPLSPTAFIDSILRESEPTPAASNTAPMDTTGAQAPAL
PTPSTPEKCLSVACLDKNELSDHLDAMDSNLDNLQTMLTSHGFSVDTSALLDLFSPSVTM
PDMSLPDLDSSLASIQELLSPQEPPRPIEAENSNPDSGKQLVHYTAQPLFLLDPDAVDTG
SSELPVLFELGESSYFSEGDDYTDDPTISLLTGTEPHKAKDPTVS

BDBM72283

n/a

Name

BDBM72283

Synonyms:

2-[2-[2,5-bis(chloranyl)phenyl]sulfanylethanoylamino]-N-[2,3,4-tris(fluoranyl)phenyl]ethanamide | 2-[[2-(2,5-dichlorophenyl)sulfanylacetyl]amino]-N-(2,3,4-trifluorophenyl)acetamide | 2-[[2-[(2,5-dichlorophenyl)thio]-1-oxoethyl]amino]-N-(2,3,4-trifluorophenyl)acetamide | 2-[[2-[(2,5-dichlorophenyl)thio]acetyl]amino]-N-(2,3,4-trifluorophenyl)acetamide | MLS000335853 | SMR000253607 | cid_2560700

Type

Small organic molecule

Emp. Form.

C16H11Cl2F3N2O2S

Mol. Mass.

423.237

SMILES

Fc1ccc(NC(=O)CNC(=O)CSc2cc(Cl)ccc2Cl)c(F)c1F

Structure