Ki Summary

Reaction Details

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Target

Neuropeptides B/W receptor type 1

Ligand

BDBM75910

Substrate/Competitor

n/a

Meas. Tech.

Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)

IC50

2700±n/a nM

Citation

PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Neuropeptides B/W receptor type 1

Name:

Neuropeptides B/W receptor type 1

Synonyms:

GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

36111.82

Organism:

Homo sapiens (Human)

Description:

gi_119607128

Residue:

328

Sequence:

MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA

BDBM75910

n/a

Name

BDBM75910

Synonyms:

5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)-4-pyridazinecarboxylic acid methyl ester | 6-keto-5-(4-methoxyphenoxy)-1-p-cumenyl-pyridazine-4-carboxylic acid methyl ester | SR-02000000434 | SR-02000000434-1 | cid_46835813 | methyl 5-(4-methoxyphenoxy)-6-oxidanylidene-1-(4-propan-2-ylphenyl)pyridazine-4-carboxylate | methyl 5-(4-methoxyphenoxy)-6-oxo-1-(4-propan-2-ylphenyl)pyridazine-4-carboxylate

Type

Small organic molecule

Emp. Form.

C22H22N2O5

Mol. Mass.

394.4205

SMILES

COC(=O)c1cnn(-c2ccc(cc2)C(C)C)c(=O)c1Oc1ccc(OC)cc1

Structure