Ki Summary

Reaction Details

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Target

Neuropeptides B/W receptor type 1

Ligand

BDBM75927

Substrate/Competitor

n/a

Meas. Tech.

Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)

IC50

2100±n/a nM

Citation

PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Neuropeptides B/W receptor type 1

Name:

Neuropeptides B/W receptor type 1

Synonyms:

GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

36111.82

Organism:

Homo sapiens (Human)

Description:

gi_119607128

Residue:

328

Sequence:

MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA

BDBM75927

n/a

Name

BDBM75927

Synonyms:

N-[4-(5-chloro-3-keto-2-p-cumenyl-pyridazin-4-yl)oxyphenyl]acetamide | N-[4-[5-chloranyl-3-oxidanylidene-2-(4-propan-2-ylphenyl)pyridazin-4-yl]oxyphenyl]ethanamide | N-[4-[5-chloro-3-oxo-2-(4-propan-2-ylphenyl)pyridazin-4-yl]oxyphenyl]acetamide | N-[4-[[5-chloro-3-oxo-2-(4-propan-2-ylphenyl)-4-pyridazinyl]oxy]phenyl]acetamide | SR-02000000461 | SR-02000000461-1 | cid_46835800

Type

Small organic molecule

Emp. Form.

C21H20ClN3O3

Mol. Mass.

397.855

SMILES

CC(C)c1ccc(cc1)-n1ncc(Cl)c(Oc2ccc(NC(C)=O)cc2)c1=O

Structure