Ki Summary

Reaction Details

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Target

Neuropeptides B/W receptor type 1

Ligand

BDBM75933

Substrate/Competitor

n/a

Meas. Tech.

Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7)

IC50

4400±n/a nM

Citation

PubChem, PC Late-stage fluorescence-based dose response cell-based screening assay to identify antagonists of the G-protein coupled receptor 7 (GPR7) PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Neuropeptides B/W receptor type 1

Name:

Neuropeptides B/W receptor type 1

Synonyms:

GPR7 | NPBW1_HUMAN | NPBWR1 | neuropeptides B/W receptor 1

Type:

Enzyme Catalytic Domain

Mol. Mass.:

36111.82

Organism:

Homo sapiens (Human)

Description:

gi_119607128

Residue:

328

Sequence:

MDNASFSEPWPANASGPDPALSCSNASTLAPLPAPLAVAVPVVYAVICAVGLAGNSAVLY
VLLRAPRMKTVTNLFILNLAIADELFTLVLPINIADFLLRQWPFGELMCKLIVAIDQYNT
FSSLYFLTVMSADRYLVVLATAESRRVAGRTYSAARAVSLAVWGIVTLVVLPFAVFARLD
DEQGRRQCVLVFPQPEAFWWRASRLYTLVLGFAIPVSTICVLYTTLLCRLHAMRLDSHAK
ALERAKKRVTFLVVAILAVCLLCWTPYHLSTVVALTTDLPQTPLVIAISYFITSLSYANS
CLNPFLYAFLDASFRRNLRQLITCRAAA

BDBM75933

n/a

Name

BDBM75933

Synonyms:

SR-02000000469 | SR-02000000469-1 | [1-(2,3-dichlorobenzyl)-2-piperidyl]-[4-(4-nitrophenyl)piperazino]methanone | [1-[(2,3-dichlorophenyl)methyl]-2-piperidinyl]-[4-(4-nitrophenyl)-1-piperazinyl]methanone | [1-[(2,3-dichlorophenyl)methyl]piperidin-2-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone | [1-[[2,3-bis(chloranyl)phenyl]methyl]piperidin-2-yl]-[4-(4-nitrophenyl)piperazin-1-yl]methanone | cid_46846316

Type

Small organic molecule

Emp. Form.

C23H26Cl2N4O3

Mol. Mass.

477.384

SMILES

[O-][N+](=O)c1ccc(cc1)N1CCN(CC1)C(=O)C1CCCCN1Cc1cccc(Cl)c1Cl

Structure