Ki Summary

Reaction Details

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Target

Photoreceptor-specific nuclear receptor

Ligand

BDBM39727

Substrate/Competitor

n/a

Meas. Tech.

TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists

IC50

4745±n/a nM

Citation

PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Photoreceptor-specific nuclear receptor

Name:

Photoreceptor-specific nuclear receptor

Synonyms:

NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor

Type:

PROTEIN

Mol. Mass.:

44699.83

Organism:

Homo sapiens (Human)

Description:

ChEMBL_401901

Residue:

410

Sequence:

METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN

BDBM39727

n/a

Name

BDBM39727

Synonyms:

2-(2-naphthalenyloxy)-N-[2-[[2-(2-naphthalenyloxy)-1-oxoethyl]amino]ethyl]acetamide | 2-(2-naphthoxy)-N-[2-[[2-(2-naphthoxy)acetyl]amino]ethyl]acetamide | 2-naphthalen-2-yloxy-N-[2-(2-naphthalen-2-yloxyethanoylamino)ethyl]ethanamide | 2-naphthalen-2-yloxy-N-[2-[(2-naphthalen-2-yloxyacetyl)amino]ethyl]acetamide | MLS000534009 | N,N'-1,2-ethanediylbis[2-(2-naphthyloxy)acetamide] | SMR000141445 | cid_1787421

Type

Small organic molecule

Emp. Form.

C26H24N2O4

Mol. Mass.

428.4798

SMILES

O=C(COc1ccc2ccccc2c1)NCCNC(=O)COc1ccc2ccccc2c1

Structure