| Reaction Details |
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 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
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| Ligand | BDBM75993 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists |
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| IC50 | 3619±n/a nM |
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| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Photoreceptor-specific nuclear receptor |
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| Name: | Photoreceptor-specific nuclear receptor |
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| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44699.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_401901 |
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| Residue: | 410 |
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| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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| BDBM75993 |
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| n/a |
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| Name | BDBM75993 |
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| Synonyms: | 5-bromanyl-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]furan-2-carboxamide | 5-bromo-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]-2-furamide | 5-bromo-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]-2-furancarboxamide | 5-bromo-N-[4-([1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl]furan-2-carboxamide | MLS000685772 | SMR000324292 | cid_7217822 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H10BrN5O2 |
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| Mol. Mass. | 384.187 |
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| SMILES | Brc1ccc(o1)C(=O)Nc1ccc(cc1)-c1ccc2nncn2n1 |
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| Structure | 
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