| Reaction Details |
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 | Report a problem with these data |
| Target | Photoreceptor-specific nuclear receptor |
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| Ligand | BDBM58809 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists |
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| IC50 | 1426±n/a nM |
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| Citation |  PubChem, PC TR-FRET-based biochemical high throughput dose response assay to identify NR2E3 inverse agonists PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Photoreceptor-specific nuclear receptor |
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| Name: | Photoreceptor-specific nuclear receptor |
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| Synonyms: | NR2E3 | NR2E3_HUMAN | PNR | RNR | photoreceptor-specific nuclear receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44699.83 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_401901 |
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| Residue: | 410 |
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| Sequence: | METRPTALMSSTVAAAAPAAGAASRKESPGRWGLGEDPTGVSPSLQCRVCGDSSSGKHYG
IYACNGCSGFFKRSVRRRLIYRCQVGAGMCPVDKAHRNQCQACRLKKCLQAGMNQDAVQN
ERQPRSTAQVHLDSMESNTESRPESLVAPPAPAGRSPRGPTPMSAARALGHHFMASLITA
ETCAKLEPEDADENIDVTSNDPEFPSSPYSSSSPCGLDSIHETSARLLFMAVKWAKNLPV
FSSLPFRDQVILLEEAWSELFLLGAIQWSLPLDSCPLLAPPEASAAGGAQGRLTLASMET
RVLQETISRFRALAVDPTEFACMKALVLFKPETRGLKDPEHVEALQDQSQVMLSQHSKAH
HPSQPVRFGKLLLLLPSLRFITAERIELLFFRKTIGNTPMEKLLCDMFKN
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| BDBM58809 |
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| n/a |
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| Name | BDBM58809 |
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| Synonyms: | 2-(2,4-dichlorophenoxy)-N-[4-(6-morpholin-4-ylpyridazin-3-yl)phenyl]acetamide | 2-(2,4-dichlorophenoxy)-N-[4-(6-morpholinopyridazin-3-yl)phenyl]acetamide | 2-(2,4-dichlorophenoxy)-N-[4-[6-(4-morpholinyl)-3-pyridazinyl]phenyl]acetamide | 2-[2,4-bis(chloranyl)phenoxy]-N-[4-(6-morpholin-4-ylpyridazin-3-yl)phenyl]ethanamide | MLS001236672 | SMR000812774 | cid_18581268 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H20Cl2N4O3 |
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| Mol. Mass. | 459.325 |
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| SMILES | Clc1ccc(OCC(=O)Nc2ccc(cc2)-c2ccc(nn2)N2CCOCC2)c(Cl)c1 |
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| Structure | 
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