| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase 1 |
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| Ligand | BDBM53139 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay |
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| IC50 | 2970±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS hits from a small molecule inhibitors of mouse intestinal alkaline phosphatase via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase 1 |
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| Name: | Intestinal-type alkaline phosphatase 1 |
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| Synonyms: | Alpi | PPBI1_RAT |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 58396.39 |
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| Organism: | Rattus norvegicus (Rat) |
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| Description: | P15693 |
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| Residue: | 540 |
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| Sequence: | MQGDWVLLLLLGLRIHLSFGVIPVEEENPVFWNQKAKEALDVAKKLQPIQTSAKNLILFL
GDGMGVPTVTATRILKGQLGGHLGPETPLAMDHFPFTALSKTYNVDRQVPDSAGTATAYL
CGVKANYKTIGVSAAARFNQCNSTFGNEVFSVMHRAKKAGKSVGVVTTTRVQHASPAGTY
AHTVNRDWYSDADMPSSALQEGCKDIATQLISNMDIDVILGGGRKFMFPKGTPDPEYPGD
SDQSGVRLDSRNLVEEWLAKYQGTRYVWNREQLMQASQDPAVTRLMGLFEPTEMKYDVNR
NASADPSLAEMTEVAVRLLSRNPQGFYLFVEGGRIDQGHHAGTAYLALTEAVMFDSAIEK
ASQLTNEKDTLTLITADHSHVFAFGGYTLRGTSIFGLAPLNAQDGKSYTSILYGNGPGYV
LNSGNRPNVTDAESGDVNYKQQAAVPLSSETHGGEDVAIFARGPQAHLVHGVQEQNYIAH
VMAFAGCLEPYTDCGLAPPADENRPTTPVQNSAITMNNVLLSLQLLVSMLLLVGTALVVS
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| BDBM53139 |
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| n/a |
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| Name | BDBM53139 |
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| Synonyms: | 4-[[(E)-3-(2-furyl)acryloyl]thiocarbamoylamino]benzoic acid | 4-[[(E)-3-(furan-2-yl)prop-2-enoyl]carbamothioylamino]benzoic acid | 4-[[[[(E)-3-(2-furanyl)-1-oxoprop-2-enyl]amino]-sulfanylidenemethyl]amino]benzoic acid | MLS001163780 | SMR000539235 | cid_947839 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H12N2O4S |
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| Mol. Mass. | 316.332 |
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| SMILES | OC(=O)c1ccc(NC(=S)NC(=O)C=Cc2ccco2)cc1 |w:14.14| |
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| Structure | 
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