| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM75630 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay - Set 2 |
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| EC50 | 23200±n/a nM |
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| Citation |  PubChem, PC Dose Response concentration confirmation of uHTS hits from a small molecule activators of human intestinal alkaline phosphatase via a luminescent assay - Set 2 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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| BDBM75630 |
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| n/a |
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| Name | BDBM75630 |
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| Synonyms: | (4E)-2-(1H-benzimidazol-2-yl)-4-(dimethylaminomethylene)-5-methyl-2-pyrazolin-3-one | (4E)-2-(1H-benzimidazol-2-yl)-4-(dimethylaminomethylidene)-5-methyl-3-pyrazolone | (4E)-2-(1H-benzimidazol-2-yl)-4-(dimethylaminomethylidene)-5-methyl-pyrazol-3-one | (4E)-2-(1H-benzimidazol-2-yl)-4-(dimethylaminomethylidene)-5-methylpyrazol-3-one | MLS000719044 | SMR000291312 | cid_6484377 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H15N5O |
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| Mol. Mass. | 269.3018 |
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| SMILES | CN(C)C=c1c(=C)[nH]n(-c2nc3ccccc3[nH]2)c1=O |w:3.2| |
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| Structure | 
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