| Reaction Details |
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 | Report a problem with these data |
| Target | Intestinal-type alkaline phosphatase |
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| Ligand | BDBM50606 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase |
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| EC50 | 64400±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS activators of Mouse Intestinal Alkaline Phosphatase using Human Intestinal Alkaline Phosphatase PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Intestinal-type alkaline phosphatase |
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| Name: | Intestinal-type alkaline phosphatase |
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| Synonyms: | ALPI | Alkaline phosphatase, intestinal | Intestinal alkaline phosphatase | PPBI_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 56804.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1278525 |
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| Residue: | 528 |
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| Sequence: | MQGPWVLLLLGLRLQLSLGVIPAEEENPAFWNRQAAEALDAAKKLQPIQKVAKNLILFLG
DGLGVPTVTATRILKGQKNGKLGPETPLAMDRFPYLALSKTYNVDRQVPDSAATATAYLC
GVKANFQTIGLSAAARFNQCNTTRGNEVISVMNRAKQAGKSVGVVTTTRVQHASPAGTYA
HTVNRNWYSDADMPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPADA
SQNGIRLDGKNLVQEWLAKHQGAWYVWNRTELMQASLDQSVTHLMGLFEPGDTKYEIHRD
PTLDPSLMEMTEAALRLLSRNPRGFYLFVEGGRIDHGHHEGVAYQALTEAVMFDDAIERA
GQLTSEEDTLTLVTADHSHVFSFGGYTLRGSSIFGLAPSKAQDSKAYTSILYGNGPGYVF
NSGVRPDVNESESGSPDYQQQAAVPLSSETHGGEDVAVFARGPQAHLVHGVQEQSFVAHV
MAFAACLEPYTACDLAPPACTTDAAHPVAASLPLLAGTLLLLGASAAP
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| BDBM50606 |
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| n/a |
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| Name | BDBM50606 |
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| Synonyms: | 5-amino-6-[(Z)-(3-hydroxy-4-keto-cyclohexa-2,5-dien-1-ylidene)methyl]-3-phenyl-thiazolo[3,2-a]pyrimidin-7-one | 5-amino-6-[(Z)-(3-hydroxy-4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-3-phenyl-7-thiazolo[3,2-a]pyrimidinone | 5-amino-6-[(Z)-(3-hydroxy-4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one | 5-azanyl-6-[(Z)-(3-oxidanyl-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)methyl]-3-phenyl-[1,3]thiazolo[3,2-a]pyrimidin-7-one | 6-[1-(3,4-Dihydroxy-phenyl)-meth-(Z)-ylidene]-5-imino-3-phenyl-5,6-dihydro-thiazolo[3,2-a]pyrimidin-7-o ne | MLS000777785 | SMR000414271 | cid_16681968 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H13N3O3S |
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| Mol. Mass. | 363.39 |
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| SMILES | Nc1c(\C=C2\C=CC(=O)C(O)=C2)c(=O)nc2scc(-c3ccccc3)n12 |c:5,10| |
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| Structure | 
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