| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM48245 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay |
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| IC50 | 2620±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM48245 |
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| n/a |
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| Name | BDBM48245 |
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| Synonyms: | (E)-3-(2-methoxy-4-nitro-anilino)-1-(2-thienyl)prop-2-en-1-one | (E)-3-(2-methoxy-4-nitroanilino)-1-thiophen-2-yl-2-propen-1-one | (E)-3-(2-methoxy-4-nitroanilino)-1-thiophen-2-ylprop-2-en-1-one | (E)-3-[(2-methoxy-4-nitro-phenyl)amino]-1-thiophen-2-yl-prop-2-en-1-one | 3-[(2-methoxy-4-nitrophenyl)amino]-1-(2-thienyl)-2-propen-1-one | MLS000537797 | SMR000144035 | cid_5739690 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H12N2O4S |
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| Mol. Mass. | 304.321 |
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| SMILES | COc1cc(ccc1N=CCC(=O)c1cccs1)[N+]([O-])=O |w:8.8| |
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| Structure | 
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