Reaction Details |
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Target | Sentrin-specific protease 8 |
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Ligand | BDBM70961 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay |
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IC50 | 4970±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Sentrin-specific protease 8 |
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Name: | Sentrin-specific protease 8 |
Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 24104.52 |
Organism: | Homo sapiens (Human) |
Description: | gi_262118306 |
Residue: | 212 |
Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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BDBM70961 |
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n/a |
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Name | BDBM70961 |
Synonyms: | (6,7-dimethoxy-1-isoquinolinyl)(4,5-dimethoxy-2-nitrophenyl)methanone | (6,7-dimethoxy-1-isoquinolinyl)-(4,5-dimethoxy-2-nitrophenyl)methanone | (6,7-dimethoxy-1-isoquinolyl)-(4,5-dimethoxy-2-nitro-phenyl)methanone | (6,7-dimethoxyisoquinolin-1-yl)-(4,5-dimethoxy-2-nitro-phenyl)methanone | (6,7-dimethoxyisoquinolin-1-yl)-(4,5-dimethoxy-2-nitrophenyl)methanone | MLS000672395 | SMR000296000 | cid_286873 |
Type | Small organic molecule |
Emp. Form. | C20H18N2O7 |
Mol. Mass. | 398.3661 |
SMILES | COc1cc(C(=O)c2nccc3cc(OC)c(OC)cc23)c(cc1OC)[N+]([O-])=O |
Structure |
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