| Reaction Details |
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 | Report a problem with these data |
| Target | Sentrin-specific protease 8 |
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| Ligand | BDBM61195 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay |
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| IC50 | 2120±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for inhibitors of Sentrin-specific protease 8 (SENP8) using a Luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Sentrin-specific protease 8 |
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| Name: | Sentrin-specific protease 8 |
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| Synonyms: | DEN1 | NEDP1 | PRSC2 | SENP8 | SENP8_HUMAN | SUMO/sentrin specific peptidase family member 8 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 24104.52 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_262118306 |
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| Residue: | 212 |
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| Sequence: | MDPVVLSYMDSLLRQSDVSLLDPPSWLNDHIIGFAFEYFANSQFHDCSDHVSFISPEVTQ
FIKCTSNPAEIAMFLEPLDLPNKRVVFLAINDNSNQAAGGTHWSLLVYLQDKNSFFHYDS
HSRSNSVHAKQVAEKLEAFLGRKGDKLAFVEEKAPAQQNSYDCGMYVICNTEALCQNFFR
QQTESLLQLLTPAYITKKRGEWKDLITTLAKK
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| BDBM61195 |
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| n/a |
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| Name | BDBM61195 |
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| Synonyms: | MLS000765857 | N'-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)-4-nitro-benzohydrazide | N'-(2,6-dipyrrolidin-1-ylpyrimidin-4-yl)-4-nitrobenzohydrazide | N'-(2,6-dipyrrolidinopyrimidin-4-yl)-4-nitro-benzohydrazide | N'-[2,6-bis(1-pyrrolidinyl)-4-pyrimidinyl]-4-nitrobenzohydrazide | SMR000278963 | cid_3121369 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H23N7O3 |
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| Mol. Mass. | 397.431 |
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| SMILES | [O-][N+](=O)c1ccc(cc1)C(=O)NNc1cc(nc(n1)N1CCCC1)N1CCCC1 |
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| Structure | 
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