| Reaction Details |
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 | Report a problem with these data |
| Target | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Ligand | BDBM52712 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase. |
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| IC50 | 211±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS inhibitors of Mouse Intestinal Alkaline Phosphatase using Tissue Nonspecific Alkaline Phosphatase. PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Alkaline phosphatase, tissue-nonspecific isozyme |
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| Name: | Alkaline phosphatase, tissue-nonspecific isozyme |
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| Synonyms: | ALPL | PPBT_HUMAN | tissue-nonspecific alkaline phosphatase precursor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 57306.17 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1448917 |
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| Residue: | 524 |
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| Sequence: | MISPFLVLAIGTCLTNSLVPEKEKDPKYWRDQAQETLKYALELQKLNTNVAKNVIMFLGD
GMGVSTVTAARILKGQLHHNPGEETRLEMDKFPFVALSKTYNTNAQVPDSAGTATAYLCG
VKANEGTVGVSAATERSRCNTTQGNEVTSILRWAKDAGKSVGIVTTTRVNHATPSAAYAH
SADRDWYSDNEMPPEALSQGCKDIAYQLMHNIRDIDVIMGGGRKYMYPKNKTDVEYESDE
KARGTRLDGLDLVDTWKSFKPRYKHSHFIWNRTELLTLDPHNVDYLLGLFEPGDMQYELN
RNNVTDPSLSEMVVVAIQILRKNPKGFFLLVEGGRIDHGHHEGKAKQALHEAVEMDRAIG
QAGSLTSSEDTLTVVTADHSHVFTFGGYTPRGNSIFGLAPMLSDTDKKPFTAILYGNGPG
YKVVGGERENVSMVDYAHNNYQAQSAVPLRHETHGGEDVAVFSKGPMAHLLHGVHEQNYV
PHVMAYAACIGANLGHCAPASSAGSLAAGPLLLALALYPLSVLF
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| BDBM52712 |
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| n/a |
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| Name | BDBM52712 |
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| Synonyms: | (3E)-4-chloranyl-7-methyl-3-(5-oxidanylidene-2-sulfanylidene-imidazolidin-4-ylidene)-1H-indol-2-one | (3E)-4-chloro-3-(5-keto-2-thioxo-imidazolidin-4-ylidene)-7-methyl-oxindole | (3E)-4-chloro-7-methyl-3-(5-oxo-2-sulfanylidene-4-imidazolidinylidene)-1H-indol-2-one | (3E)-4-chloro-7-methyl-3-(5-oxo-2-sulfanylideneimidazolidin-4-ylidene)-1H-indol-2-one | (3Z)-4-chloro-7-methyl-3-(5-oxo-2-thioxoimidazolidin-4-ylidene)-1,3-dihydro-2H-indol-2-one | MLS000682961 | SMR000313044 | cid_5413620 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H8ClN3O2S |
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| Mol. Mass. | 293.729 |
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| SMILES | Cc1ccc(Cl)c2\C(C(=O)Nc12)=C1/NC(=S)NC1=O |
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| Structure | 
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