| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-7 |
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| Ligand | BDBM77496 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 |
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| EC50 | >85275±n/a nM |
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| Citation |  PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Caspase-7 |
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| Name: | Caspase-7 |
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| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
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| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
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|
|
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| BDBM77496 |
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| n/a |
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| Name | BDBM77496 |
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| Synonyms: | 2,2-Dimethyl-5-(5-methyl-furan-2-yl)-2,3,5,6-tetrahydro-1H-benzo[a]phenanthridin-4-one | 2,2-dimethyl-5-(5-methyl-2-furanyl)-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one | 2,2-dimethyl-5-(5-methyl-2-furyl)-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one | 2,2-dimethyl-5-(5-methylfuran-2-yl)-1,3,5,6-tetrahydrobenzo[a]phenanthridin-4-one | MLS000525463 | SMR000115937 | cid_3107511 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H23NO2 |
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| Mol. Mass. | 357.4449 |
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| SMILES | Cc1ccc(o1)C1Nc2ccc3ccccc3c2C2=C1C(=O)CC(C)(C)C2 |c:21| |
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| Structure | 
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