| Reaction Details |
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 | Report a problem with these data |
| Target | Caspase-7 |
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| Ligand | BDBM57513 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 |
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| EC50 | >85267±n/a nM |
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| Citation |  PubChem, PC Counterscreen for procaspase-3 activators: absorbance-based biochemical high throughput dose response assay for activators of procaspase-7 PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Caspase-7 |
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| Name: | Caspase-7 |
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| Synonyms: | Apoptotic protease Mch-3 | CASP-7 | CASP7 | CASP7_HUMAN | CMH-1 | Caspase | MCH3 | caspase 7, apoptosis-related cysteine peptidase |
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| Type: | Enzyme |
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| Mol. Mass.: | 34273.91 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55210 |
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| Residue: | 303 |
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| Sequence: | MADDQGCIEEQGVEDSANEDSVDAKPDRSSFVPSLFSKKKKNVTMRSIKTTRDRVPTYQY
NMNFEKLGKCIIINNKNFDKVTGMGVRNGTDKDAEALFKCFRSLGFDVIVYNDCSCAKMQ
DLLKKASEEDHTNAACFACILLSHGEENVIYGKDGVTPIKDLTAHFRGDRCKTLLEKPKL
FFIQACRGTELDDGIQADSGPINDTDANPRYKIPVEADFLFAYSTVPGYYSWRSPGRGSW
FVQALCSILEEHGKDLEIMQILTRVNDRVARHFESQSDDPHFHEKKQIPCVVSMLTKELY
FSQ
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|
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| BDBM57513 |
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| n/a |
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| Name | BDBM57513 |
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| Synonyms: | (3Z)-2-keto-N'-[(E)-(6-ketocyclohexa-2,4-dien-1-ylidene)methyl]-3-spiro[2,4-dihydroisoquinoline-3,1'-cyclopentane]-1-ylidene-propionohydrazide | (3Z)-2-oxidanylidene-N'-[(E)-(6-oxidanylidenecyclohexa-2,4-dien-1-ylidene)methyl]-3-spiro[2,4-dihydroisoquinoline-3,1'-cyclopentane]-1-ylidene-propanehydrazide | (3Z)-2-oxo-N'-[(E)-(6-oxo-1-cyclohexa-2,4-dienylidene)methyl]-3-(1-spiro[2,4-dihydroisoquinoline-3,1'-cyclopentane]ylidene)propanehydrazide | (3Z)-2-oxo-N'-[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]-3-spiro[2,4-dihydroisoquinoline-3,1'-cyclopentane]-1-ylidenepropanehydrazide | MLS000589649 | SMR000219463 | cid_6506668 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H23N3O3 |
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| Mol. Mass. | 389.447 |
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| SMILES | Oc1ccccc1C=NNC(=O)C(=O)CC1=NC2(CCCC2)Cc2ccccc12 |w:8.9,t:16| |
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| Structure | 
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