| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Ligand | BDBM71904 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
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| IC50 | 7300±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM10 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 10303.50 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285809906 |
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| Residue: | 93 |
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| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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| BDBM71904 |
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| n/a |
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| Name | BDBM71904 |
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| Synonyms: | 3-Methyl-2-[2-(5-nitro-furan-2-yl)-vinyl]-3H-quinazolin-4-one | 3-methyl-2-[(E)-2-(5-nitro-2-furanyl)ethenyl]-4-quinazolinone | 3-methyl-2-[(E)-2-(5-nitro-2-furyl)vinyl]quinazolin-4-one | 3-methyl-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one | MLS000529350 | SMR000121825 | cid_5731073 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H11N3O4 |
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| Mol. Mass. | 297.2655 |
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| SMILES | Cn1c(\C=C\c2ccc(o2)[N+]([O-])=O)nc2ccccc2c1=O |
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| Structure | 
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