Ki Summary

Reaction Details

Report a problem with these data

Target

Mitochondrial import inner membrane translocase subunit TIM10

Ligand

BDBM78151

Substrate/Competitor

n/a

Meas. Tech.

Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay

IC50

3340±n/a nM

Citation

PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Mitochondrial import inner membrane translocase subunit TIM10

Name:

Mitochondrial import inner membrane translocase subunit TIM10

Synonyms:

MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ...

Type:

Enzyme Catalytic Domain

Mol. Mass.:

10303.50

Organism:

Saccharomyces cerevisiae S288c

Description:

gi_285809906

Residue:

Sequence:

MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF

BDBM78151

n/a

Name

BDBM78151

Synonyms:

4-chloro-N'-[(4-chlorobenzoyl)oxy]benzenecarboximidamide | 4-chlorobenzoic acid [(Z)-[amino-(4-chlorophenyl)methylene]amino] ester | 4-chlorobenzoic acid [(Z)-[amino-(4-chlorophenyl)methylidene]amino] ester | MLS000578025 | SMR000187210 | [(Z)-[amino-(4-chlorophenyl)methylidene]amino] 4-chlorobenzoate | [(Z)-[azanyl-(4-chlorophenyl)methylidene]amino] 4-chloranylbenzoate | cid_9567277

Type

Small organic molecule

Emp. Form.

C14H10Cl2N2O2

Mol. Mass.

309.147

SMILES

NC(=NOC(=O)c1ccc(Cl)cc1)c1ccc(Cl)cc1 |w:2.2|

Structure