| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Ligand | BDBM78193 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
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| IC50 | 1410±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM10 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 10303.50 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285809906 |
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| Residue: | 93 |
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| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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| BDBM78193 |
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| n/a |
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| Name | BDBM78193 |
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| Synonyms: | 2-(4-chlorophenyl)acetic acid [(Z)-[1-amino-2-(2,4-dichlorophenyl)ethylidene]amino] ester | MLS000563950 | SMR000176883 | [(Z)-[1-amino-2-(2,4-dichlorophenyl)ethylidene]amino] 2-(4-chlorophenyl)acetate | [(Z)-[1-azanyl-2-(2,4-dichlorophenyl)ethylidene]amino] 2-(4-chlorophenyl)ethanoate | cid_9594348 |
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| Type | Small organic molecule |
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| Emp. Form. | C16H13Cl3N2O2 |
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| Mol. Mass. | 371.646 |
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| SMILES | NC(Cc1ccc(Cl)cc1Cl)=NOC(=O)Cc1ccc(Cl)cc1 |w:11.12| |
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| Structure | 
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