| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Ligand | BDBM11297 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
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| IC50 | 4550±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM10 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
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| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 10303.50 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285809906 |
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| Residue: | 93 |
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| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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| BDBM11297 |
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| n/a |
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| Name | BDBM11297 |
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| Synonyms: | 4,6-dimethyl-2-[(4-methylbenzene)sulfonyl]-5-nitropyridine-3-carbonitrile | Compound 1 analog 8 | acs.jmedchem.1c00409_ST.544 | cid_2726176 |
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| Type | Small organic molecule |
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| Emp. Form. | C15H13N3O4S |
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| Mol. Mass. | 331.346 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)c1nc(C)c(c(C)c1C#N)[N+]([O-])=O |
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| Structure | 
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