Reaction Details |
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Target | Mitochondrial import inner membrane translocase subunit TIM10 |
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Ligand | BDBM78421 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay |
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IC50 | 7090±n/a nM |
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Citation | PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1 yeast via a luminescent assay PubChem Bioassay(2010)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Mitochondrial import inner membrane translocase subunit TIM10 |
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Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 10303.50 |
Organism: | Saccharomyces cerevisiae S288c |
Description: | gi_285809906 |
Residue: | 93 |
Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
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BDBM78421 |
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n/a |
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Name | BDBM78421 |
Synonyms: | 1-(5-chloranyl-2-methoxy-phenyl)-3-[2-(4-fluorophenyl)ethyl]thiourea | 1-(5-chloro-2-methoxy-phenyl)-3-[2-(4-fluorophenyl)ethyl]thiourea | 1-(5-chloro-2-methoxyphenyl)-3-[2-(4-fluorophenyl)ethyl]thiourea | MLS001224330 | SMR000678476 | cid_17297684 |
Type | Small organic molecule |
Emp. Form. | C16H16ClFN2OS |
Mol. Mass. | 338.827 |
SMILES | COc1ccc(Cl)cc1NC(=S)NCCc1ccc(F)cc1 |
Structure |
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