| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
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| Ligand | BDBM78670 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
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| IC50 | 2493±208 nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| Ubiquitin-conjugating enzyme E2 N |
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| Name: | Ubiquitin-conjugating enzyme E2 N |
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| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17137.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101440 |
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| Residue: | 152 |
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| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
|
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|
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| BDBM78670 |
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| n/a |
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| Name | BDBM78670 |
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| Synonyms: | 1-ethyl-3-[(2-oxidanylidene-5-propan-2-yl-indol-3-yl)amino]thiourea | 1-ethyl-3-[(2-oxo-5-propan-2-yl-3-indolyl)amino]thiourea | 1-ethyl-3-[(2-oxo-5-propan-2-ylindol-3-yl)amino]thiourea | 1-ethyl-3-[(5-isopropyl-2-keto-indol-3-yl)amino]thiourea | MLS000339580 | SMR000241997 | cid_6277813 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H18N4OS |
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| Mol. Mass. | 290.384 |
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| SMILES | CCNC(=S)NNC1=c2cc(ccc2=NC1=O)C(C)C |c:7,14| |
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| Structure | 
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