| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
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| Ligand | BDBM78671 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
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| IC50 | 664±75 nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Ubiquitin-conjugating enzyme E2 N |
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| Name: | Ubiquitin-conjugating enzyme E2 N |
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| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
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| Type: | PROTEIN |
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| Mol. Mass.: | 17137.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EBI_101440 |
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| Residue: | 152 |
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| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
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| BDBM78671 |
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| n/a |
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| Name | BDBM78671 |
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| Synonyms: | 1-[(2-keto-5-nitro-indol-3-yl)amino]-3-(tetrahydrofurfuryl)thiourea | 1-[(5-nitro-2-oxidanylidene-indol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | 1-[(5-nitro-2-oxo-3-indolyl)amino]-3-(2-oxolanylmethyl)thiourea | 1-[(5-nitro-2-oxoindol-3-yl)amino]-3-(oxolan-2-ylmethyl)thiourea | MLS000417334 | SMR000242561 | cid_5800378 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H15N5O4S |
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| Mol. Mass. | 349.365 |
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| SMILES | [O-][N+](=O)c1ccc2[N-]C(=O)C(=[NH+]NC(=S)NCC3CCCO3)c2c1 |w:11.11| |
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| Structure | 
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