| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Ubiquitin-conjugating enzyme E2 N |
|---|
| Ligand | BDBM78899 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm |
|---|
| IC50 | 1524±142 nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS for the identification of UBC13 Polyubiquitin Inhibitors via a TR-FRET Assay reconfirm PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Ubiquitin-conjugating enzyme E2 N |
|---|
| Name: | Ubiquitin-conjugating enzyme E2 N |
|---|
| Synonyms: | BLU | UBE2N | UBE2N_HUMAN | ubiquitin-conjugating enzyme E2 N |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 17137.61 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | EBI_101440 |
|---|
| Residue: | 152 |
|---|
| Sequence: | MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPE
EYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQIRTVLLSIQALLSAPNPDDP
LANDVAEQWKTNEAQAIETARAWTRLYAMNNI
|
|
|
|---|
| BDBM78899 |
|---|
| n/a |
|---|
| Name | BDBM78899 |
|---|
| Synonyms: | 1-(2-methoxyethyl)-3-[(5-nitro-2-oxidanylidene-indol-3-yl)amino]thiourea | 1-(2-methoxyethyl)-3-[(5-nitro-2-oxo-3-indolyl)amino]thiourea | 1-(2-methoxyethyl)-3-[(5-nitro-2-oxoindol-3-yl)amino]thiourea | 1-[(2-keto-5-nitro-indol-3-yl)amino]-3-(2-methoxyethyl)thiourea | MLS000759991 | SMR000370042 | cid_6055390 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H13N5O4S |
|---|
| Mol. Mass. | 323.328 |
|---|
| SMILES | COCCNC(=S)N[NH+]=C1C(=O)[N-]c2ccc(cc12)[N+]([O-])=O |w:8.7| |
|---|
| Structure | 
|
|---|
Search and Browse
