BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetPerilipin-1
LigandBDBM66043
Substrate/Competitorn/a
Meas. Tech.Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain
IC50 6794±n/a nM
Citation PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Perilipin-1
Name:Perilipin-1
Synonyms:PERI | PLIN | PLIN1 | PLIN1_HUMAN
Type:Enzyme Catalytic Domain
Mol. Mass.:55988.69
Organism:Homo sapiens (Human)
Description:gi_223718203
Residue:522
Sequence:
MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEK
GVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTI
STRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARA
LEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTD
TEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGM
AGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDID
NPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAP
RPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM66043
n/a
NameBDBM66043
Synonyms:2-hydroxy-3-[(E)-3-(2-hydroxy-3-methoxy-phenyl)acryloyl]-6-methyl-pyran-4-one | 2-hydroxy-3-[(E)-3-(2-hydroxy-3-methoxyphenyl)-1-oxoprop-2-enyl]-6-methyl-4-pyranone | 2-hydroxy-3-[(E)-3-(2-hydroxy-3-methoxyphenyl)prop-2-enoyl]-6-methylpyran-4-one | 3-[(E)-3-(3-methoxy-2-oxidanyl-phenyl)prop-2-enoyl]-6-methyl-2-oxidanyl-pyran-4-one | 4-hydroxy-3-[3-(2-hydroxy-3-methoxyphenyl)acryloyl]-6-methyl-2H-pyran-2-one | MLS000530155 | SMR000135132 | cid_5717503
TypeSmall organic molecule
Emp. Form.C16H14O6
Mol. Mass.302.2788
SMILESCOc1cccc(C=CC(=O)c2c(O)cc(C)oc2=O)c1O |w:7.6|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: