| Reaction Details |
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 | Report a problem with these data |
| Target | Perilipin-1 |
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| Ligand | BDBM79418 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain |
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| IC50 | 1227±n/a nM |
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| Citation |  PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Perilipin-1 |
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| Name: | Perilipin-1 |
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| Synonyms: | PERI | PLIN | PLIN1 | PLIN1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55988.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_223718203 |
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| Residue: | 522 |
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| Sequence: | MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEK
GVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTI
STRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARA
LEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTD
TEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGM
AGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDID
NPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAP
RPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
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| BDBM79418 |
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| n/a |
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| Name | BDBM79418 |
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| Synonyms: | (4Z)-3-(4-methylphenyl)-4-[(E)-3-phenylprop-2-enylidene]-1,2-oxazol-5-one | (4Z)-3-(4-methylphenyl)-4-[(E)-3-phenylprop-2-enylidene]-5-isoxazolone | (4Z)-4-[(E)-3-phenylprop-2-enylidene]-3-(p-tolyl)-2-isoxazolin-5-one | 3-(4-methylphenyl)-4-(3-phenyl-2-propen-1-ylidene)-5(4H)-isoxazolone | MLS000684313 | SMR000267897 | cid_2263521 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H15NO2 |
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| Mol. Mass. | 289.3279 |
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| SMILES | Cc1ccc(cc1)C1=NOC(=O)\C1=C/C=C/c1ccccc1 |t:8| |
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| Structure | 
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