Reaction Details |
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Target | Perilipin-1 |
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Ligand | BDBM79419 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain |
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IC50 | 2068±n/a nM |
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Citation | PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Perilipin-1 |
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Name: | Perilipin-1 |
Synonyms: | PERI | PLIN | PLIN1 | PLIN1_HUMAN |
Type: | Enzyme Catalytic Domain |
Mol. Mass.: | 55988.69 |
Organism: | Homo sapiens (Human) |
Description: | gi_223718203 |
Residue: | 522 |
Sequence: | MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEK
GVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTI
STRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARA
LEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTD
TEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGM
AGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDID
NPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAP
RPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
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BDBM79419 |
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n/a |
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Name | BDBM79419 |
Synonyms: | (4Z)-1-(2-furanylmethyl)-2-methyl-4-[(4-nitrophenyl)methylidene]-5-oxo-3-pyrrolecarboxylic acid methyl ester | (4Z)-1-(2-furfuryl)-5-keto-2-methyl-4-(4-nitrobenzylidene)-2-pyrroline-3-carboxylic acid methyl ester | MLS000674921 | SMR000291966 | cid_2185539 | methyl (4Z)-1-(furan-2-ylmethyl)-2-methyl-4-[(4-nitrophenyl)methylidene]-5-oxidanylidene-pyrrole-3-carboxylate | methyl (4Z)-1-(furan-2-ylmethyl)-2-methyl-4-[(4-nitrophenyl)methylidene]-5-oxopyrrole-3-carboxylate | methyl 1-(2-furylmethyl)-2-methyl-4-(4-nitrobenzylidene)-5-oxo-4,5-dihydro-1H-pyrrole-3-carboxylate |
Type | Small organic molecule |
Emp. Form. | C19H16N2O6 |
Mol. Mass. | 368.3401 |
SMILES | COC(=O)C1=C(C)N(Cc2ccco2)C(=O)\C1=C/c1ccc(cc1)[N+]([O-])=O |c:4| |
Structure |
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