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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Perilipin-1 | ||
| Ligand | BDBM66575 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain | ||
| IC50 | 2278±n/a nM | ||
| Citation |  PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) PubChem Bioassay(2011)[AID] | ||
| More Info.: | Get all data from this article, Solution Info, Assay Method | ||
| Perilipin-1 | |||
| Name: | Perilipin-1 | ||
| Synonyms: | PERI | PLIN | PLIN1 | PLIN1_HUMAN | ||
| Type: | Enzyme Catalytic Domain | ||
| Mol. Mass.: | 55988.69 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_223718203 | ||
| Residue: | 522 | ||
| Sequence: |
| ||
| BDBM66575 | |||
| n/a | |||
| Name | BDBM66575 | ||
| Synonyms: | (4Z)-3-(4-chlorophenyl)-4-(4-hydroxybenzylidene)isoxazol-5(4H)-one | 3-(4-chlorophenyl)-4-[(4-ketocyclohexa-2,5-dien-1-ylidene)methyl]-3-isoxazolin-5-one | 3-(4-chlorophenyl)-4-[(4-oxidanylidenecyclohexa-2,5-dien-1-ylidene)methyl]-2H-1,2-oxazol-5-one | 3-(4-chlorophenyl)-4-[(4-oxo-1-cyclohexa-2,5-dienylidene)methyl]-2H-isoxazol-5-one | 3-(4-chlorophenyl)-4-[(4-oxocyclohexa-2,5-dien-1-ylidene)methyl]-2H-1,2-oxazol-5-one | MLS000686375 | SMR000313218 | cid_5337766 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C16H10ClNO3 | ||
| Mol. Mass. | 299.708 | ||
| SMILES | Clc1ccc(cc1)-c1[nH]oc(=O)c1C=C1C=CC(=O)C=C1 |c:17,21,(5.23,-5.36,;5.23,-3.82,;6.57,-3.05,;6.57,-1.51,;5.23,-.74,;3.9,-1.51,;3.9,-3.05,;5.23,.8,;3.99,1.71,;4.46,3.17,;6,3.17,;6.91,4.42,;6.48,1.71,;7.94,1.23,;9.09,2.26,;8.77,3.77,;9.91,4.8,;11.38,4.33,;12.52,5.36,;11.7,2.82,;10.55,1.79,)| | ||
| Structure | 
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