| Reaction Details |
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 | Report a problem with these data |
| Target | Perilipin-1 |
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| Ligand | BDBM48899 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain |
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| IC50 | 21420±n/a nM |
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| Citation |  PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Perilipin-1 |
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| Name: | Perilipin-1 |
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| Synonyms: | PERI | PLIN | PLIN1 | PLIN1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55988.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_223718203 |
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| Residue: | 522 |
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| Sequence: | MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEK
GVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTI
STRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARA
LEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTD
TEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGM
AGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDID
NPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAP
RPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
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| BDBM48899 |
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| n/a |
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| Name | BDBM48899 |
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| Synonyms: | (E)-2-(2,3-Dihydro-indole-1-carbonyl)-3-(4-hydroxy-3-methoxy-phenyl)-acrylonitrile | (E)-2-(2,3-dihydroindol-1-ylcarbonyl)-3-(3-methoxy-4-oxidanyl-phenyl)prop-2-enenitrile | (E)-2-(2,3-dihydroindole-1-carbonyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enenitrile | (E)-2-[2,3-dihydroindol-1-yl(oxo)methyl]-3-(4-hydroxy-3-methoxyphenyl)-2-propenenitrile | (E)-3-(4-hydroxy-3-methoxy-phenyl)-2-(indoline-1-carbonyl)acrylonitrile | MLS000779135 | SMR000415839 | cid_1975835 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16N2O3 |
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| Mol. Mass. | 320.3419 |
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| SMILES | COc1cc(\C=C(/C#N)C(=O)N2CCc3ccccc23)ccc1O |
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| Structure | 
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