| Reaction Details |
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 | Report a problem with these data |
| Target | Perilipin-1 |
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| Ligand | BDBM50085363 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain |
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| IC50 | 1868±n/a nM |
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| Citation |  PubChem, PC Luminescence-based biochemical high throughput dose response assay for inhibitors of the interaction of the lipase co-activator protein, abhydrolase domain containing 5 (ABHD5) with perilipin-1 (PLIN1) (2K validation set) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Perilipin-1 |
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| Name: | Perilipin-1 |
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| Synonyms: | PERI | PLIN | PLIN1 | PLIN1_HUMAN |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 55988.69 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_223718203 |
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| Residue: | 522 |
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| Sequence: | MAVNKGLTLLDGDLPEQENVLQRVLQLPVVSGTCECFQKTYTSTKEAHPLVASVCNAYEK
GVQSASSLAAWSMEPVVRRLSTQFTAANELACRGLDHLEEKIPALQYPPEKIASELKDTI
STRLRSARNSISVPIASTSDKVLGAALAGCELAWGVARDTAEFAANTRAGRLASGGADLA
LGSIEKVVEYLLPPDKEESAPAPGHQQAQKSPKAKPSLLSRVGALTNTLSRYTVQTMARA
LEQGHTVAMWIPGVVPLSSLAQWGASVAMQAVSRRRSEVRVPWLHSLAAAQEEDHEDQTD
TEGEDTEEEEELETEENKFSEVAALPGPRGLLGGVAHTLQKTLQTTISAVTWAPAAVLGM
AGRVLHLTPAPAVSSTKGRAMSLSDALKGVTDNVVDTVVHYVPLPRLSLMEPESEFRDID
NPPAEVERREAERRASGAPSAGPEPAPRLAQPRRSLRSAQSPGAPPGPGLEDEVATPAAP
RPGFPAVPREKPKRRVSDSFFRPSVMEPILGRTHYSQLRKKS
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| BDBM50085363 |
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| n/a |
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| Name | BDBM50085363 |
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| Synonyms: | CHEMBL60718 | L-1-Tosylamido-2-phenylethyl chloromethyl ketone | N-Tosyl-L-phenylalanine chloromethyl ketone | N-Tosyl-L-phenylalanyl chloromethyl ketone | N-[(2S)-4-chloro-3-oxo-1-phenylbutan-2-yl]-4-methylbenzenesulfonamide | TPCK | Tos-Phe-CH2Cl | Tosylphenylalanyl chloromethyl ketone | cid_439647 | l-N-(alpha-(Chloroacetyl)phenethyl)-p-toluenesulfonamide |
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| Type | Small organic molecule |
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| Emp. Form. | C17H18ClNO3S |
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| Mol. Mass. | 351.848 |
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| SMILES | Cc1ccc(cc1)S(=O)(=O)N[C@@H](Cc1ccccc1)C(=O)CCl |r| |
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| Structure | 
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