| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Ligand | BDBM77730 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim23-1: a luminescent tim10-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Name: | Mitochondrial import inner membrane translocase subunit TIM10 |
|---|
| Synonyms: | MRS11 | TIM10 | TIM10_YEAST | TPA: Essential protein of the mitochondrial intermembrane space | TPA: Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that delivers hydrophobic proteins to the TIM22 complex for insertion into the inner ... |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 10303.50 |
|---|
| Organism: | Saccharomyces cerevisiae S288c |
|---|
| Description: | gi_285809906 |
|---|
| Residue: | 93 |
|---|
| Sequence: | MSFLGFGGGQPQLSSQQKIQAAEAELDLVTDMFNKLVNNCYKKCINTSYSEGELNKNESS
CLDRCVAKYFETNVQVGENMQKMGQSFNAAGKF
|
|
|
|---|
| BDBM77730 |
|---|
| n/a |
|---|
| Name | BDBM77730 |
|---|
| Synonyms: | 4-methyl-N-[(2-methyl-1H-indol-5-yl)methyl]-3-nitro-benzamide | 4-methyl-N-[(2-methyl-1H-indol-5-yl)methyl]-3-nitrobenzamide | MLS000724615 | SMR000237468 | cid_4107216 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H17N3O3 |
|---|
| Mol. Mass. | 323.3459 |
|---|
| SMILES | Cc1cc2cc(CNC(=O)c3ccc(C)c(c3)[N+]([O-])=O)ccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
