| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM79660 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | >71412±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM79660 |
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| n/a |
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| Name | BDBM79660 |
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| Synonyms: | (4Z)-4-[[(2-chlorobenzyl)amino]methylene]-5-(trifluoromethyl)-2-pyrazolin-3-one | (4Z)-4-[[(2-chlorophenyl)methylamino]methylidene]-3-(trifluoromethyl)-1H-pyrazol-5-one | 4-{[(2-chlorobenzyl)amino]methylene}-5-(trifluoromethyl)-2,4-dihydro-3H-pyrazol-3-one | MLS000594319 | SMR000126499 | cid_5913053 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H9ClF3N3O |
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| Mol. Mass. | 303.668 |
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| SMILES | FC(F)(F)c1[nH][nH]c(=O)c1C=NCc1ccccc1Cl |w:11.12| |
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| Structure | 
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