| Reaction Details |
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 | Report a problem with these data |
| Target | Tropomyosin alpha-1 chain |
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| Ligand | BDBM47297 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) |
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| EC50 | 40044±n/a nM |
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| Citation |  PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Tropomyosin alpha-1 chain |
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| Name: | Tropomyosin alpha-1 chain |
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| Synonyms: | TPM1 | TPM1_PIG | cardiac alpha tropomyosin |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 32681.01 |
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| Organism: | Sus scrofa |
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| Description: | P42639 |
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| Residue: | 284 |
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| Sequence: | MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
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| BDBM47297 |
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| n/a |
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| Name | BDBM47297 |
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| Synonyms: | 3-(4-bromophenyl)-5-[4-(dimethylamino)phenyl]-N-methyl-2-pyrazoline-1-carbothioamide | 3-(4-bromophenyl)-5-[4-(dimethylamino)phenyl]-N-methyl-4,5-dihydro-1H-pyrazole-1-carbothioamide | 5-(4-bromophenyl)-3-[4-(dimethylamino)phenyl]-N-methyl-3,4-dihydropyrazole-2-carbothioamide | MLS000625076 | SMR000293859 | cid_2953219 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H21BrN4S |
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| Mol. Mass. | 417.366 |
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| SMILES | CNC(=S)N1N=C(CC1c1ccc(cc1)N(C)C)c1ccc(Br)cc1 |c:5| |
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| Structure | 
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