BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTropomyosin alpha-1 chain
LigandBDBM79714
Substrate/Competitorn/a
Meas. Tech.Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50>71550±n/a nM
Citation PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tropomyosin alpha-1 chain
Name:Tropomyosin alpha-1 chain
Synonyms:TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:Enzyme Catalytic Domain
Mol. Mass.:32681.01
Organism:Sus scrofa
Description:P42639
Residue:284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM79714
n/a
NameBDBM79714
Synonyms:(2-allyloxy-5-bromo-benzyl)-ethyl-amine;hydrochloride | MLS000679986 | N-[(5-bromanyl-2-prop-2-enoxy-phenyl)methyl]ethanamine;hydrochloride | N-[(5-bromo-2-prop-2-enoxyphenyl)methyl]ethanamine;hydrochloride | N-[2-(allyloxy)-5-bromobenzyl]ethanamine hydrochloride | SMR000296878 | cid_2983409
TypeSmall organic molecule
Emp. Form.C12H16BrNO
Mol. Mass.270.166
SMILESCCNCc1cc(Br)ccc1OCC=C
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: