Ki Summary

Reaction Details

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Target

Tropomyosin alpha-1 chain

Ligand

BDBM46792

Substrate/Competitor

n/a

Meas. Tech.

Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)

EC50

4888±n/a nM

Citation

PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID]

More Info.:

Get all data from this article, Solution Info, Assay Method

Tropomyosin alpha-1 chain

Name:

Tropomyosin alpha-1 chain

Synonyms:

TPM1 | TPM1_PIG | cardiac alpha tropomyosin

Type:

Enzyme Catalytic Domain

Mol. Mass.:

32681.01

Organism:

Sus scrofa

Description:

P42639

Residue:

284

Sequence:

MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI

BDBM46792

n/a

Name

BDBM46792

Synonyms:

2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(3,5-dimethoxy-4-oxidanylidene-cyclohexa-2,5-dien-1-ylidene)propanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(3,5-dimethoxy-4-oxo-1-cyclohexa-2,5-dienylidene)propanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(3,5-dimethoxy-4-oxocyclohexa-2,5-dien-1-ylidene)propanenitrile | 2-(1,3-dihydrobenzimidazol-2-ylidene)-3-(4-keto-3,5-dimethoxy-cyclohexa-2,5-dien-1-ylidene)propionitrile | MLS000716138 | SMR000277655 | cid_5335875

Type

Small organic molecule

Emp. Form.

C18H15N3O3

Mol. Mass.

321.33

SMILES

COc1cc(C=C(C#N)c2nc3ccccc3[nH]2)cc(OC)c1O

Structure