BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetTropomyosin alpha-1 chain
LigandBDBM79716
Substrate/Competitorn/a
Meas. Tech.Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF)
EC50>71462±n/a nM
Citation PubChem, PC Fluorescence-based biochemical high throughput dose response assay for activators of the calcium sensitivity of cardiac Regulated Thin Filaments (RTF) PubChem Bioassay(2011)[AID]
More Info.:Get all data from this article,   Solution Info,  Assay Method
 
Tropomyosin alpha-1 chain
Name:Tropomyosin alpha-1 chain
Synonyms:TPM1 | TPM1_PIG | cardiac alpha tropomyosin
Type:Enzyme Catalytic Domain
Mol. Mass.:32681.01
Organism:Sus scrofa
Description:P42639
Residue:284
Sequence:
MDAIKKKMQMLKLDKENALDRAEQAEADKKAAEDRSKRLEDELVSLQKKLKATEDELDKY
SEAPKDAQEKLELAEKKATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAA
DESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYEEVARKLVIIESDLERAE
ERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDKYEEEIKVLSDKLKEAETRAE
FAERSVTKLEKSIDDLEDELYAQKLKYKAISEELDHALNDMTSI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM79716
n/a
NameBDBM79716
Synonyms:4-[[1-(4-chloranyl-3-methyl-phenyl)sulfonylpiperidin-3-yl]carbonylamino]benzoic acid | 4-[[1-(4-chloro-3-methyl-phenyl)sulfonylnipecotoyl]amino]benzoic acid | 4-[[1-(4-chloro-3-methylphenyl)sulfonylpiperidine-3-carbonyl]amino]benzoic acid | 4-[[[1-(4-chloro-3-methylphenyl)sulfonyl-3-piperidinyl]-oxomethyl]amino]benzoic acid | MLS000716052 | SMR000277569 | cid_3230755
TypeSmall organic molecule
Emp. Form.C20H21ClN2O5S
Mol. Mass.436.909
SMILESCc1cc(ccc1Cl)S(=O)(=O)N1CCCC(C1)C(=O)Nc1ccc(cc1)C(O)=O
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least: