Reaction Details |
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Target | Orexin/Hypocretin receptor type 1 |
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Ligand | BDBM79793 |
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Substrate/Competitor | n/a |
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Meas. Tech. | Fluorescence-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) |
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IC50 | 1457±n/a nM |
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Citation | PubChem, PC Fluorescence-based cell-based high throughput dose response assay for antagonists of the orexin 1 receptor (OX1R; HCRTR1) PubChem Bioassay(2011)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Orexin/Hypocretin receptor type 1 |
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Name: | Orexin/Hypocretin receptor type 1 |
Synonyms: | HCRTR1 | Hypocretin receptor type 1 | OX1R_HUMAN | Orexin receptor type 1 | Orexin receptor type 1 (OR 1) | Orexin receptor type 1 (OR-1) | Orexin receptor type 1 (OX1) | Orexin receptor type 1 (OX1R) | Orexin receptor type 1 (OxR1) | Ox1r |
Type: | Protein |
Mol. Mass.: | 47554.50 |
Organism: | Homo sapiens (Human) |
Description: | O43613 |
Residue: | 425 |
Sequence: | MEPSATPGAQMGVPPGSREPSPVPPDYEDEFLRYLWRDYLYPKQYEWVLIAAYVAVFVVA
LVGNTLVCLAVWRNHHMRTVTNYFIVNLSLADVLVTAICLPASLLVDITESWLFGHALCK
VIPYLQAVSVSVAVLTLSFIALDRWYAICHPLLFKSTARRARGSILGIWAVSLAIMVPQA
AVMECSSVLPELANRTRLFSVCDERWADDLYPKIYHSCFFIVTYLAPLGLMAMAYFQIFR
KLWGRQIPGTTSALVRNWKRPSDQLGDLEQGLSGEPQPRARAFLAEVKQMRARRKTAKML
MVVLLVFALCYLPISVLNVLKRVFGMFRQASDREAVYACFTFSHWLVYANSAANPIIYNF
LSGKFREQFKAAFSCCLPGLGPCGSLKAPSPRSSASHKSLSLQSRCSISKISEHVVLTSV
TTVLP
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BDBM79793 |
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n/a |
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Name | BDBM79793 |
Synonyms: | 3-Methyl-benzofuran-2-carboxylic acid (4-morpholin-4-yl-phenyl)-amide | 3-methyl-N-(4-morpholin-4-ylphenyl)-1-benzofuran-2-carboxamide | 3-methyl-N-(4-morpholinophenyl)coumarilamide | 3-methyl-N-[4-(4-morpholinyl)phenyl]-2-benzofurancarboxamide | MLS000035891 | SMR000010089 | cid_647689 |
Type | Small organic molecule |
Emp. Form. | C20H20N2O3 |
Mol. Mass. | 336.3844 |
SMILES | Cc1c(oc2ccccc12)C(=O)Nc1ccc(cc1)N1CCOCC1 |
Structure |
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