| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
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| Ligand | BDBM34419 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen |
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| Temperature | 298.15±n/a K |
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| IC50 | >100000±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
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| BDBM34419 |
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| n/a |
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| Name | BDBM34419 |
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| Synonyms: | 2,6-di-tert-butyl-4-{[4-(2-hydroxyethyl)-1-piperazinyl]carbonothioyl}phenol | 2,6-ditert-butyl-4-[[4-(2-hydroxyethyl)-1-piperazinyl]-mercaptomethylidene]-1-cyclohexa-2,5-dienone | 2,6-ditert-butyl-4-[[4-(2-hydroxyethyl)piperazin-1-yl]-sulfanyl-methylidene]cyclohexa-2,5-dien-1-one | 2,6-ditert-butyl-4-[[4-(2-hydroxyethyl)piperazin-1-yl]-sulfanylmethylidene]cyclohexa-2,5-dien-1-one | 2,6-ditert-butyl-4-[[4-(2-hydroxyethyl)piperazino]-mercapto-methylene]cyclohexa-2,5-dien-1-one | MLS000050217 | SMR000077360 | cid_5649484 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H34N2O2S |
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| Mol. Mass. | 378.572 |
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| SMILES | CC(C)(C)c1cc(cc(c1O)C(C)(C)C)C(=S)N1CCN(CCO)CC1 |
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| Structure | 
|
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