| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Ligand | BDBM34548 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen |
|---|
| Temperature | 298.15±n/a K |
|---|
| IC50 | >100000±n/a nM |
|---|
| Comments | extracted |
|---|
| Citation |  PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay(2011)[AID] |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 23013.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | gi_21955158 |
|---|
| Residue: | 199 |
|---|
| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
|
|
|---|
| BDBM34548 |
|---|
| n/a |
|---|
| Name | BDBM34548 |
|---|
| Synonyms: | 4-(3-pyridinyl)-2-sulfanylidene-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile | 4-(3-pyridyl)-2-thioxo-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile | 4-pyridin-3-yl-2-sulfanylidene-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile | MLS000108243 | SMR000104204 | cid_869514 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13N3S |
|---|
| Mol. Mass. | 267.349 |
|---|
| SMILES | S=c1[nH]c2CCCCc2c(-c2cccnc2)c1C#N |
|---|
| Structure | 
|
|---|
Search and Browse
