| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Ligand | BDBM80121 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen |
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| Temperature | 298.15±n/a K |
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| IC50 | >100000±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
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| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
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|
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| BDBM80121 |
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| n/a |
|---|
| Name | BDBM80121 |
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| Synonyms: | 2-sulfanylidene-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile | 2-thioxo-5,6,7,8-tetrahydro-1H-quinoline-3-carbonitrile | MLS000392017 | SMR000102537 | cid_1713148 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C10H10N2S |
|---|
| Mol. Mass. | 190.265 |
|---|
| SMILES | S=c1[nH]c2CCCCc2cc1C#N |
|---|
| Structure | 
|
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