| Reaction Details |
|---|
 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Ligand | BDBM48646 |
|---|
| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen |
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| Temperature | 298.15±n/a K |
|---|
| IC50 | >100000±n/a nM |
|---|
| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of APOBEC3G DNA Deaminase Inhibitors via a A3A counterscreen PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| |
| DNA dC->dU-editing enzyme APOBEC-3A |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Synonyms: | ABC3A_HUMAN | APOBEC3A | probable DNA dC->dU-editing enzyme APOBEC-3A |
|---|
| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23013.77 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_21955158 |
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| Residue: | 199 |
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| Sequence: | MEASPASGPRHLMDPHIFTSNFNNGIGRHKTYLCYEVERLDNGTSVKMDQHRGFLHNQAK
NLLCGFYGRHAELRFLDLVPSLQLDPAQIYRVTWFISWSPCFSWGCAGEVRAFLQENTHV
RLRIFAARIYDYDPLYKEALQMLRDAGAQVSIMTYDEFKHCWDTFVDHQGCPFQPWDGLD
EHSQALSGRLRAILQNQGN
|
|
|
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| BDBM48646 |
|---|
| n/a |
|---|
| Name | BDBM48646 |
|---|
| Synonyms: | 4-Ethyl-1-mercapto-7,8-dihydro-4H,6H-9-thia-2,3,4,9b-tetraaza-cyclopenta[b]-as-indacen-5-one | MLS000552199 | SMR000145913 | cid_913030 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C12H12N4OS2 |
|---|
| Mol. Mass. | 292.38 |
|---|
| SMILES | CCn1c2n[nH]c(=S)n2c2sc3CCCc3c2c1=O |
|---|
| Structure | 
|
|---|
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